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American Journal of Speech-Language Pathology Vol.4 152-158 November 1995.
© American Speech-Language-Hearing Association
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Cognitive Gains and Losses of Patients With Alzheimer's Disease During Frequent Practice

Argye Elizabeth Hillis 1
Lisa Benzing 2
Cathy Epstein 2

Constantine Lyketsos 3
1 Johns Hopkins University School of Medicine and The Department of Cognitive Science
2 Johns Hopkins University Department of Cognitive Science
3 Johns Hopkins University School of Medicine, Department of Psychiatry

This longitudinal study of two patients with Alzheimer's disease (AD), on 12 experimental tasks, was designed to identify a measure of cognitive decline in AD patients that would be sensitive to change over short periods (weeks), resistant to practice (repeated testing over a few weeks), and predictive of change over longer periods on standardized tests. During the periods of frequent testing, both patients improved on most tasks, but performance on the tasks of spelling words and spelling pseudowords declined in both patients during periods when they deteriorated on standardized testing. It is concluded that simple spelling tasks may provide a good baseline of the rate of cognitive decline to identify effects of intervention, at least in some AD patients.

Key Words: dysgraphia, Alzheimer's disease, dementia


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