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American Journal of Speech-Language Pathology Vol.17 401-415 November 2008. doi:10.1044/1058-0360(2008/07-0047)
© American Speech-Language-Hearing Association
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Tutorial

Defining, Identifying, and Evaluating Clinical Trials of Stuttering Treatments: A Tutorial for Clinicians

Mark Onslow
Australian Stuttering Research Centre, The University of Sydney

Mark Jones
Queensland Clinical Trials Centre, University of Queensland, Australia

Sue O'Brian
Ross Menzies
Ann Packman
Australian Stuttering Research Centre, The University of Sydney

Contact author: Mark Onslow, Australian Stuttering Research Centre, The University of Sydney, Gate 2 East Street, Lidcombe, NSW, Australia. E-mail: m.onslow{at}usyd.edu.au.

Purpose: To develop a method for clinicians to evaluate stuttering treatment efficacy research with very little burden of work.

Method: The clinical trial is the most fundamental, clinically interpretable, and useful output unit of stuttering treatment research. We define a clinical trial of a stuttering treatment and specify 3 levels of clinical trials evidence. We use this taxonomy to identify and evaluate clinical trials of stuttering treatment. Our taxonomy draws on 2 fundamental principles of clinical trials used to evaluate health care: randomization and effect size.

Results: Published clinical trials of stuttering treatments were identified and allocated to 1 of 3 levels of evidence.

Conclusions: We outline a 3-step, semi-automated, Internet-based method to identify the publication of a report of stuttering treatment efficacy. For a report identified as such, a 10-item checklist is applied to verify its status as a clinical trial and to allocate it to 1 of 3 levels of clinical trials evidence. The present taxonomy reduces the burden of work of a 136-item checklist in an existing taxonomy.

Key Words: stuttering severity, children, adults, clinical trials, efficacy


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